Clinical Challenge: Dark Lesion on Lower Lip MPR Differential Diagnosis of Pigmented Lesions in the Oral Mucosa: A Clinical Based Overview and Narrative Review What Caused These Multiple Hyperpigmented Macules of the Mouth? Treatment of labial melanotic macules on the lip. These are benign spots that appear on the lips for no apparent reason. The causes are mostly genetic, but similar spots can appear in smokers, after Labial Lentigo (labial melanotic macule) Cancer Therapy Advisor
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