New in the August 14, 2025, issue of NEJM: CagrilintideSemaglutide for Overweight or Obesity (REDEFINE 1 phase 3a trial) Cagrilintide Semaglutide for Overweight and Diabetes (REDEFINE 2 phase 3a trial) Efficacy and safety of once weekly semaglutide 24 mg versus placebo in people with obesity and prediabetes (STEP 10): a randomised, double blind, placebo controlled, multicentre phase 3 trial Cagrilintide & Semaglutide in Overweight Diabetics (REDEFINE 2) NEJM Med Journal Club Weight Loss Efficacy of Cagrilintide and Semaglutide gutsandgrowth Treat to target in weight management with semaglutide: Realworld evidence from an eHealth clinic Seier 2025 Diabetes, Obesity and Metabolism Wiley Online Library
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