Glucose 6 Phosphate: Metabolism and Functions G6PD Deficiency Glucose 6 phosphate dehydrogenase deficiency X linked recessive disorder Leads to low NADPH, impairing glutathione regeneration RBCs are vulnerable to oxidative damage Pathophysiology: In G6PD deficiency: No Glucose 6 Phosphate Dehydrogenase an overview ScienceDirect Topics Erythrocyte glutathione enzymatic pathway vector illustration graphic Premium Vector Clinical associations and potential cellular mechanisms linking G6PD deficiency and atherosclerotic cardiovascular disease npj Metabolic Health and Disease