Depigmentation Therapies: Exploring Biochemical Pathways, Classification and Medical Interventions for Skin Health Tyrosinase inhibitors are key ingredients for addressing hyperpigmentation issues like post inflammatory hyperpigmentation (PIH) and post inflammatory erythema (PIE). To understand how they work, it's helpful to know that PIH is a dark spot Glutathione Master Antioxidant & Detoxification Full article: Novel tyrosinase inhibitory peptide with free radical scavenging ability Table 2 from Tyrosinase Inhibition Assay and Skin Whitening Cream Formulation of Edamame Extract ( Glycine Max ) Semantic Scholar