Prolonged Administration of Melatonin Ameliorates Liver Phenotypes in Cholestatic Murine Model Cellular and Molecular Gastroenterology and Hepatology Dr. As we age, our cells can become more stressed; the production of Glutathione (GSH) decreases and can even stop. As cells are subjected to oxidative stress, the production process can't This figure illustrates the actions of melatonin in reducing free Download Scientific Diagram Integrative Model of Oxidative Stress Adaptation in the Fungal Pathogen Candida albicans PLOS One NRF2 Rewires Cellular Metabolism to Support the Antioxidant Response IntechOpen