Pigmented Lesions of the Oral Cavity Oral and Maxillofacial Surgery Clinics Oral Melanotic Macule MEDizzy An oral melanotic macule is a harmless dark spot found on the lip, most often the lower lip, or inside the mouth, either on the gums, inside the cheek, or on the roof of the mouth. An oral melanotic Happy Wednesday! , In this video, a patients labial melanotic macule (a benign pigmented lesion) is being treated with liquid nitrogen. Labial melanotic macules are flat and asymmetrical with a A Case Report of Oral Malignant Melanoma: A Silent Killer Cureus