Cagrilintide and semaglutide together drive record weight loss in global trial Cagrilintide: The Next Gen Peptide for Weight Loss and Satiety Hubmed Coadministered Cagrilintide and Semaglutide in Adults with Overweight or Obesity New England Journal of Medicine Safety, tolerability, pharmacokinetics, and pharmacodynamics of concomitant administration of multiple doses of cagrilintide with semaglutide 24 mg for weight management: a randomised, controlled, phase 1b trial The Lancet In the REDEFINE 2 phase 3a trial involving adults with obesity and diabetes, the use of cagrilintidesemaglutide resulted in a significantly lower body weight than placebo at 68 weeks. Full trial results
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cagrilintide phase 2 New in the August 14, 2025, issue of NEJM: Cagrilintide–Semaglutide for Overweight or Obesity (REDEFINE 1 phase 3a trial) Cagrilintide–Semaglutide for Overweight and Diabetes (REDEFINE 2 phase 3a trial)