3 Glutathione Rescue Normally, glutathione binds NAPQI and converts it into non toxic byproducts (cysteine + mercapturic acid) that are excreted. Example: Glutathione is your liver's safety net against toxins. Solved The stepwise mechanism below shows how glutathione Chegg.com Acetaminophen metabolism and NAPQI mediated mitochondrial effects Download Scientific Diagram PDF] Evidence that Increased Acetaminophen use in Genetically Vulnerable Children Appears to be a Major Cause of the Epidemics of Autism, Attention Deficit with Hyperactivity, and Asthma Semantic Scholar PXR ribosylation at E194 amplifies NAPQI in acetaminopheninduced liver injury in mice, rescued by Schisandrin B Acta Pharmacologica Sinica