TMAO metaorganismal pathway and chronic inflammatory diseases Full article: Trimethylamine N oxide formation, the bacterial taxa involved and intervention strategies to reduce its concentration in the human body Trimethylamine N oxide (TMAO) is a small molecule produced in humans primarily by the gut liver axis and has become an important biomarker, and possible mediator, of cardiometabolic and renal disease. Dietary choline, phosphatidylcholine ( Trimethylamine N oxide, The Important Therapeutic Target for Heart Failure Unraveling the Formation Mechanisms of Trimethylamine N Oxide and Its Inhibition by Food Ingredients: Toward Cardioprotective Food Development Journal of Agricultural and Food Chemistry