Pigmented Lesions Pocket Dentistry This patient has multiple labial melanotic macules. These are essentially freckles of the lips. These most commonly involve the lower lip. This patient had involvement of both the upper and lower lips. Black and Brown: Non neoplastic Pigmentation of the Oral Mucosa Head and Neck Pathology Springer Nature Link Labial melanotic macule Oral melanoma and other pigmentations: when to biopsy? Lambertini 2018 Journal of the European Academy of Dermatology and Venereology Wiley Online Library