MRP1 Dependent Extracellular Release of Glutathione Induces Cardiomyocyte Ferroptosis After Ischemia Reperfusion Circulation Research YouTube Glutathione is one of the most important molecules in detoxification. It drives Phase II conjugation and helps neutralize oxidative stress at the cellular level. But detoxification does not end with transformation. It The structural basis for regulation of the glutathione transporter Ycf1 by regulatory domain phosphorylation Nature Communications Glutathione S transferase enzymes detoxify xenobiotics
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